Article
[Congestive heart failure is a common disease with complex inheritance--new perspectives through genome wide association studies].
Der Internist - 1 Apr 2008
Linsel-Nitschke P, Schunkert H, Erdmann J
Abstract excerpt
Congestive heart failure can be defined as a complex syndrome comprising the end stage of multiple cardiovascular disorders. Genetics of congestive heart failure focused thus far mainly on rare familiar forms of hypertrophic or dilated cardiomyopathy. These are often caused by rare and deleterious mutations showing Mendelian inheritance conferred by genes encoding largely for structural proteins of the...
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