The UCP2-866 A/A genotype is associated with low density lipoprotein particle sizes in the general population.

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Article

The UCP2-866 A/A genotype is associated with low density lipoprotein particle sizes in the general population.

Medical science monitor : international medical journal of experimental and clinical research - 1 Mar 2008

Hamada Taku, Kotani Kazuhiko, Fujiwara Shinji, Sano Yoshiko, Domichi Masayuki, Tsuzaki Kokoro, Takahashi Kaoru, Sakane Naoki

Abstract excerpt

BACKGROUND: It has been reported that a common G-->A single nucleotide polymorphism (SNP) at the position -866 of the uncoupling protein-2 promoter (UCP2-866 G/A SNP) modulates UCP2 expression in adipose tissue and pancreatic beta-cell function, and lipid profiles. Reduced low density lipoprotein (LDL) particle size is a significant predictor of the development for coronary artery disease. The purpose of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed

Identifiers

PMID: 18301352

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.