Article
Computational elucidation of potential antigenic CTL epitopes in Ebola virus.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2015
Dikhit Manas R, Kumar Santosh, Vijaymahantesh, Sahoo Bikash R, Mansuri Rani, Amit Ajay, Yousuf Ansari Md, Sahoo Ganesh C, Bimal Sanjiva, Das Pradeep
Abstract excerpt
Cell-mediated immunity is important for the control of Ebola virus infection. We hypothesized that those HLA A0201 and HLA B40 restricted epitopes derived from Ebola virus proteins, would mount a good antigenic response. Here we employed an immunoinformatics approach to identify specific 9mer amino acid which may be capable of inducing a robust cell-mediated immune response in humans. We identified a set of 28...
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