Article
Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotypes in vitro and is identical to osteopontin (secreted phosphoprotein I, 2aR).
Biochemical and biophysical research communications - 14 Jun 1991
Giachelli C, Bae N, Lombardi D, Majesky M, Schwartz S
Abstract excerpt
We have identified a rat smooth muscle cell mRNA, 2B7, which distinguishes smooth muscle cell phenotypes in vitro. Sequence and tissue distribution data strongly suggest this mRNA to be identical to osteopontin (secreted phosphoprotein I, 2aR). In vivo, 2B7 mRNA is expressed in normal rat aorta and carotid arteries at levels 50-60-fold greater than heart, and about 3-4 times the levels found in adult rat kidney...
Topics
- Amino Acid Sequence
- Angioplasty, Balloon
- Animals
- Aorta, Thoracic
- Carotid Arteries
- Cloning, Molecular
- DNA
- Genetic Markers
- Male
- Molecular Sequence Data