Article
Protective role of CYP1A1*2A in the development of multiple myeloma.
Acta haematologica - 1 Jan 2008
Kang Seong-Ho, Kim Tae Young, Kim Ho Young, Yoon Jong-Hyun, Cho Han-Ik, Yoon Sung Soo, Kang Dae Hee, Suh Cheol Won, Lee Jae Hoon, Lee Dong Soon
Abstract excerpt
We had previously reported the association of the NQO1*2/*2 polymorphism with a decreased risk for multiple myeloma (MM) in Koreans (odds ratio, OR, 0.24; 95% confidence interval, CI, 0.01-0.68). The associations of polymorphisms of other metabolizing enzymes (CYP1A1, GSTM1 and GSTT1) with the MM risk were investigated in 116 Korean MM patients and 176 Korean controls using TaqMan allelic discrimination and...
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