Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.

Histology and histopathology - 1 May 2008

Lee Li-Yu, Wu Chi-Ming, Wang Chee-Chan, Yu Jau-Song, Liang Ying, Huang Kuo-Hao, Lo Chih-Hong, Hwang Tsann-Long

Abstract excerpt

Matrix metalloproteinases (MMPs) MMP-2 and MMP-9 can degrade type IV collagen of extracellular matrix and basal membranes. Claudin-4 is a member of a large family of transmembrane proteins, claudins, essential in the formation and maintenance of tight junctions. Claudin-4 has been shown to activate MMP-2, indicating that claudin-mediated increased cancer cell invasion might be mediated through the activation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique, Indirect

Share to Lymph Nodes

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Membrane Proteins

Share to Stomach Neoplasms

Source

Identifiers

PMID: 18283635
DOI: 10.14670/HH-23.515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.PMID 18283635Read ↗

Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer.Semantic proximity Read ↗

Cdx2 transcription factor regulates claudin‐3 and claudin‐4 expression during intestinal differentiation of gastric carcinomaSemantic proximity Read ↗

Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection.Semantic proximity Read ↗

Immunohistochemical analysis of colorectal cancer with gastric phenotype: claudin-18 is associated with poor prognosis.Semantic proximity Read ↗

MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.Semantic proximity Read ↗

Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cellsSemantic proximity Read ↗

Relationship between biologic behavior and phenotypic expression in intramucosal gastric carcinomas.Semantic proximity Read ↗

Expression of CD44 containing variant exon 9 (CD44v9) in gastric adenomas and adenocarcinomas: relation to the proliferation and progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.