Article
Immunohistochemical analysis of colorectal cancer with gastric phenotype: claudin-18 is associated with poor prognosis.
Pathology international - 1 Oct 2010
Matsuda Miho, Sentani Kazuhiro, Noguchi Tsuyoshi, Hinoi Takao, Okajima Masazumi, Matsusaki Keisuke, Sakamoto Naoya, Anami Katsuhiro, Naito Yutaka, Oue Naohide, Yasui Wataru
Abstract excerpt
Claudin-18 plays a key role in constructing tight junctions, and altered claudin-18 expression has been documented in various human malignancies; however, little is known about the biological significance of claudin-18 in colorectal cancer (CRC). The aim of this study is to investigate the signif...
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