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Article

Molecular and bioinformatic evidence of hepatitis C virus evolution in brain.

The Journal of infectious diseases - 15 Feb 2008

Fishman Sarah L, Murray Jacinta M, Eng Francis J, Walewski José L, Morgello Susan, Branch Andrea D

Abstract excerpt

BACKGROUND: Neurocognitive deficits in patients with hepatitis C virus (HCV) infection prompted a search for HCV in brain. RESULTS: HCV was present in the brains of 7 (54%) of 13 patients with viremia, as determined by 5' UTR and E1 (envelope 1) gene analysis. Brain HCV RNA consensus sequences differed from those in plasma and liver in 4 (57%) of 7 patients. The quality of HCV RNA from postmortem brain and liver...

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Source

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Identifiers

PMID: 18275278
DOI: 10.1086/526519
PMCID: PMC2736634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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