Article
Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: evidence of replication.
Journal of virology - 1 Jan 2002
Radkowski Marek, Wilkinson Jeffrey, Nowicki Marek, Adair Debra, Vargas Hugo, Ingui Craig, Rakela Jorge, Laskus Tomasz
Abstract excerpt
Patients with chronic hepatitis C are more likely to have significant changes in their physical and mental well-being than patients with liver disease of other etiology, and hepatitis C virus (HCV) has been occasionally implicated in diseases of the central nervous system. We analyzed the presence of the HCV negative-strand RNA sequence, which is the viral replicative intermediary, in autopsy brain tissue samples...
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