Article
Mutation analysis of gene PAX6 in human gliomas.
Genetics and molecular research : GMR - 5 Oct 2007
Pinto G R, Clara C A, Santos M J, Almeida J R W, Burbano R R, Rey J A, Casartelli C
Abstract excerpt
Gliomas are the most common tumors of the central nervous system. In spite of the marked advances in the characterization of the molecular pathogenesis of gliomas, these tumors remain incurable and, in most of the cases, resistant to treatments, due to their molecular heterogeneity. Gene PAX6, which encodes a transcription factor that plays an important role in the development of the central nervous system, was...
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