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Article

New immuno-PCR assay for detection of low concentrations of shiga toxin 2 and its variants.

Journal of clinical microbiology - 1 Apr 2008

Zhang Wenlan, Bielaszewska Martina, Pulz Matthias, Becker Karsten, Friedrich Alexander W, Karch Helge, Kuczius Thorsten

Abstract excerpt

Shiga toxin (Stx)-producing Escherichia coli (STEC) strains secrete toxins that are major virulence factors and diagnostic targets, but some STEC strains secrete Stx in amounts that cannot be detected using conventional cell cytotoxicity or immunological assays. Therefore, there is an urgent need for more-sensitive Stx detection methods. We describe the development of an assay that can detect low concentrations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18272709
DOI: 10.1128/JCM.02271-07
PMCID: PMC2292924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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