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Article

Cortactin expression predicts poor survival in laryngeal carcinoma

12 Feb 2008

Abstract excerpt

Amplification of the 11q13 region is one of the most frequent aberrations in squamous cell carcinomas of the head and neck region (HNSCC). Amplification of 11q13 has been shown to correlate with the presence of lymph node metastases and decreased survival. The 11q13.3 amplicon carries numerous genes including cyclin D1 and cortactin. Recently, we reported that FADD becomes overexpressed upon amplification and...

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PMID: 18268491
DOI: 10.1038/sj.bjc.6604246

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