Article
Biological behaviour of an endothelial cell line (HPMEC) on vascular prostheses grafted with hydroxypropylgamma-cyclodextrine (HPgamma-CD) and hydroxypropylbeta-cyclodextrine (HPbeta-CD).
Journal of materials science. Materials in medicine - 1 Jun 2008
Blanchemain N, Chai F, Haulon S, Krump-Konvalinkova V, Traisnel M, Morcellet M, Martel B, Kirkpatrick C J, Hildebrand H F
Abstract excerpt
The cytocompatibility of cyclodextrins (CDs) grafting on vascular polyester (PET) prostheses for further loading with biomolecules was investigated in this study. Viability tests demonstrated no toxicity of HP-CDs and PolyHP-CDs at 4,000 mg/l with survival rates of 80 to 96%. Proliferation tests using the human pulmonary microvascular endothelial cell line (HPMEC-ST1) revealed an excellent biocompatibility for...
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