Article
Crystals of DhaA mutants from Rhodococcus rhodochrous NCIMB 13064 diffracted to ultrahigh resolution: crystallization and preliminary diffraction analysis.
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Feb 2008
Stsiapanava Alena, Koudelakova Tana, Lapkouski Mikalai, Pavlova Martina, Damborsky Jiri, Smatanova Ivana Kuta
Abstract excerpt
The enzyme DhaA from Rhodococcus rhodochrous NCIMB 13064 belongs to the haloalkane dehalogenases, which catalyze the hydrolysis of haloalkanes to the corresponding alcohols. The haloalkane dehalogenase DhaA and its variants can be used to detoxify the industrial pollutant 1,2,3-trichloropropane (TCP). Three mutants named DhaA04, DhaA14 and DhaA15 were constructed in order to study the importance of tunnels...
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