Article
Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up.
Journal of cutaneous medicine and surgery - 1 Jan 2000
Ross J Barrie, Finlayson Laura A, Klotz P Jennifer, Langley Richard G, Gaudet Roxanne, Thompson Kara, Churchman Sarah M, McDermott Michael F, Hawkins Philip N
Abstract excerpt
BACKGROUND: The susceptibility gene for familial cold autoinflammatory syndrome (FCAS) has been mapped to chromosome 1q44 and a point mutation determined to be present in all affected members of a large Canadian kindred. Anakinra (Kineret) is known to block IL-1 receptor and in the few patients w...
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