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Article

Screening of functional and positional candidate genes in families with common variable immunodeficiency.

BMC immunology - 7 Feb 2008

Salzer Ulrich, Neumann Carla, Thiel Jens, Woellner Cristina, Pan-Hammarström Qiang, Lougaris Vassilis, Hagena Tina, Jung Johannes, Birmelin Jennifer, Du Likun, Metin Ayse, Webster David A, Plebani Alessandro, Moschese Viviana, Hammarström Lennart, Schäffer Alejandro A, Grimbacher Bodo

Abstract excerpt

BACKGROUND: Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes. The recent discovery that some CVID patients show monogenic defects in the genes encoding ICOS, TACI or CD19 prompted us to investigate several functional candidate genes in individuals with CVID. RESULTS: The exonic, protein coding regions of the...

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Identifiers

PMID: 18254984
DOI: 10.1186/1471-2172-9-3
PMCID: PMC2268914

Genes

CCL18
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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