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Article

Do children with lupus have fewer male siblings?

Lupus - 1 Feb 2008

Moorthy L N, Peterson M G E, Onel K B, Lehman T J A

Abstract excerpt

It is widely acknowledged that genetic factors play a significant role in the pathogenesis of systemic lupus erythematosus (SLE). However, the female preponderance remains unexplained. We hypothesized that the female preponderance in childhood SLE results from selection early in the course of conception against male fetuses bearing genetic material predisposing to SLE. If this hypothesis is accurate, there should...

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Source

Identifiers

PMID: 18250136
DOI: 10.1177/0961203307085111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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