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Article

Knockdown of the L3/Lhx8 gene suppresses cholinergic differentiation of murine embryonic stem cell-derived spheres.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Apr 2008

Manabe Takayuki, Tatsumi Kouko, Inoue Masahide, Matsuyoshi Hiroko, Makinodan Manabu, Yamauchi Takahira, Makinodan Eri, Yokoyama Shohei, Sakumura Ryoko, Okuda Hiroaki, Wanaka Akio

Abstract excerpt

L3/Lhx8, a member of the Lim-homeobox gene family, is selectively and specifically expressed in the murine embryonic medial ganglionic eminence (MGE). Our previous study demonstrated that L3/Lhx8-deficient mice specifically lack cholinergic neurons in the basal forebrain. In this manuscript, we r...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18248940
DOI: 10.1016/j.ijdevneu.2007.11.004

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18248940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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