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Functional Characterization and Mutagenesis of the Proposed Behavioral Sensor TlpD of <i>Helicobacter pylori</i>

2 Feb 2008

Abstract excerpt

Helicobacter pylori requires flagellar motility and chemotaxis to establish and maintain chronic infection of the human stomach. The pH gradient in the stomach mucus is essential for bacterial orientation and guides the bacterium toward a narrow layer of the mucus, suggesting that H. pylori is capable of energy sensing or taxis. In the present study, H. pylori wild-type behavior in a temporal swimming assay could...

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PMID: 18245281
DOI: 10.1128/jb.01940-07

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