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Article

Effect of mutation of lysine-120, located at the entry to the active site of O-acetylserine sulfhydrylase-A from Salmonella typhimurium.

Biochimica et biophysica acta - 1 Apr 2008

Tai Chia-Hui, Rabeh Wael M, Guan Rong, Schnackerz Klaus D, Cook Paul F

Abstract excerpt

O-Acetylserine sulfhydrylase catalyzes the final step of the biosynthesis of L-cysteine, the replacement of the beta-acetoxy group of O-acetyl-L-serine (OAS) by a thiol. The enzyme undergoes a conformational change to close the site upon formation of the external Schiff base (ESB) with OAS. Mutat...

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Identifiers

PMID: 18243146
DOI: 10.1016/j.bbapap.2007.12.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18243146-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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