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Article

Functional significance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease.

Atherosclerosis - 1 Sept 2008

Chen Qi, Razzaghi Hamid, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

Lipoprotein lipase (LPL) plays a pivotal role in lipid metabolism by hydrolyzing triglyceride (TG)-rich lipoprotein particles. Abnormalities in normal LPL function are associated with the risk of coronary artery disease (CAD). A number of genetic variants have been identified in the LPL gene that affects different functions of the LPL protein. A common HindIII polymorphism in intron 8 (T/G) of the LPL gene has...

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Source

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Identifiers

PMID: 18242618
DOI: 10.1016/j.atherosclerosis.2007.12.011
PMCID: PMC2603421

Genes

LPL
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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