The lipoprotein lipase HindIII polymorphism: association with total cholesterol and LDL-cholesterol, but not with HDL and triglycerides in 342 females.

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Article

The lipoprotein lipase HindIII polymorphism: association with total cholesterol and LDL-cholesterol, but not with HDL and triglycerides in 342 females.

Clinical chemistry - 1 Jul 1999

Larson I, Hoffmann M M, Ordovas J M, Schaefer E J, März W, Kreuzer J

Abstract excerpt

BACKGROUND: Lipoprotein lipase (LPL) is the rate-limiting enzyme in the hydrolysis of core triglycerides in chylomicrons and VLDL. METHODS: We investigated the association between the HindIII polymorphism of the LPL gene and fasting glucose, lipid, and lipoprotein concentrations in 683 Caucasians. We first stabilized the study subjects, using an 8-day diet and exercise intervention program before obtaining blood...

Topics

Alleles
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Deoxyribonuclease HindIII
Diet
Exercise
Female
Humans
Lipoprotein Lipase
Male
Middle Aged
Phenotype
Polymorphism, Restriction Fragment Length
Sex Factors
Triglycerides

Source

Open in PubMed

Identifiers

PMID: 10388470

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