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Article

Disruption of the striated muscle glycogen-targeting subunit of protein phosphatase 1: influence of the genetic background.

Journal of molecular endocrinology - 1 Feb 2008

Paterson James, Kelsall Ian R, Cohen Patricia T W

Abstract excerpt

A prediabetic phenotype of glucose intolerance, insulin resistance and obesity was observed at approximately 12 months of age in mice homozygous for a null allele of the major skeletal muscle glycogen-targeting subunit G(M) of protein phosphatase 1 (PP1) and derived from a 129/Ola donor strain. In this study, backcrossing of these G(M)-/- mice (termed obese G(M)-/- mice) onto two different genetic backgrounds...

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Identifiers

PMID: 18234908
DOI: 10.1677/JME-07-0120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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