Article
Mutational and transcriptional analyses of an avian pathogenic Escherichia coli ColV plasmid.
BMC microbiology - 29 Jan 2008
Skyberg Jerod A, Johnson Timothy J, Nolan Lisa K
Abstract excerpt
BACKGROUND: Previously we described a 184-kb ColV plasmid, pAPEC-O2-ColV, that contributed to the ability of an E. coli to kill avian embryos, grow in human urine, and colonize the murine kidney. Here, the roles of several genes encoded by this plasmid in virulence were assessed using mutational and transcriptional analyses. METHODS: Genes chosen for deletion were iss, tsh, iutA, iroN, sitA, and cvaB. In...
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