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Article

Evolution of the iss gene in Escherichia coli.

Applied and environmental microbiology - 1 Apr 2008

Johnson Timothy J, Wannemuehler Yvonne M, Nolan Lisa K

Abstract excerpt

The increased serum survival gene iss has long been recognized for its role in extraintestinal pathogenic Escherichia coli (ExPEC) virulence. iss has been identified as a distinguishing trait of avian ExPEC but not of human ExPEC. This gene has been localized to large virulence plasmids and shares strong similarities with the bor gene from bacteriophage lambda. Here, we demonstrate that three alleles of iss occur...

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Identifiers

PMID: 18281426
DOI: 10.1128/AEM.02634-07
PMCID: PMC2293169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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