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Article

Signal integration by the two-component signal transduction response regulator CpxR.

Journal of bacteriology - 1 Apr 2008

Wolfe Alan J, Parikh Niyati, Lima Bruno P, Zemaitaitis Bozena

Abstract excerpt

The CpxAR two-component signal transduction system in Escherichia coli and other pathogens senses diverse envelope stresses and promotes the transcription of a variety of genes that remedy these stresses. An important member of the CpxAR regulon is cpxP. The CpxA-dependent transcription of cpxP has been linked to stresses such as misfolded proteins and alkaline pH. It also has been proposed that acetyl phosphate,...

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Identifiers

PMID: 18223085
DOI: 10.1128/JB.01906-07
PMCID: PMC2293188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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