Article
fMRI reveals altered auditory processing in manifest and premanifest Huntington's disease.
Neuropsychologia - 1 Apr 2008
Saft Carsten, Schüttke Anne, Beste Christian, Andrich Jürgen, Heindel Walter, Pfleiderer Bettina
Abstract excerpt
Structural alterations of the basal ganglia occur in patients with Huntington's disease (HD). The aim of this exploratory study was to assess auditory processing mechanisms by functional MRI (fMRI) in patients with premanifest (pHD) and manifest HD to gain more insight in possible alterations in basal ganglia-thalamic circuits. Sixteen HD and 18 pHD as well as corresponding age- and gender-matched controls were...
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