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Article

Apoptosis in the Homeostasis of the Immune System and in Human Immune Mediated Diseases

1 Jan 2008

Abstract excerpt

The immune system has evolved sophisticated mechanisms controlling the development of responses to dangerous antigens while avoiding unnecessary attacks to innocuous, commensal or self antigens. The risk of autoimmunity is continuously checked and balanced against the risk of succumbing to exogenous infectious agents. It is therefore of paramount importance to understand the molecular events linking the breakdown...

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PMID: 18220836
DOI: 10.2174/138161208783413310

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