Article
The complex interplay between autophagy, apoptosis, and necrotic signals promotes T‐cell homeostasis
15 Jun 2010
Abstract excerpt
Intense research efforts over the last two decades have focused on establishing the significance of apoptotic signaling in adaptive immunity. Without doubt, caspase-dependent apoptosis plays vital roles in many immune processes, including lymphocyte development, positive and negative selection, homeostasis, and self-tolerance. Cell biologists have developed new insights into cell death, establishing that other...
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