Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenomics: a tool to prevent and cure coronary heart disease.

Current pharmaceutical design - 1 Jan 2007

Candore Giuseppina, Balistreri Carmela Rita, Caruso Marco, Grimaldi Maria Paola, Incalcaterra Egle, Listì Florinda, Vasto Sonya, Caruso Calogero

Abstract excerpt

Inflammation and genetics play an important role in the pathogenesis of coronary heart disease (CHD). This is supported by epidemiological studies which have thoroughly investigated the association between CHD and gene polymorphisms of the inflammatory molecules. Moreover, efforts to find elective therapy have not been rewarding and, despite the increasing appreciation of the role of genetics in CHD and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokines
Share to Coronary Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipopolysaccharide Receptors

Share to Lipoxygenase

Share to Patient Selection

Share to Prostaglandin-Endoperoxide Synthases

Share to Receptors, Chemokine

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 18220812
DOI: 10.2174/138161207783018617

Genes

CCR5
TLR4
LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenomics: a tool to prevent and cure coronary heart disease.PMID 18220812Read ↗

Pro-inflammatory gene variants in myocardial infarction and longevity: implications for pharmacogenomics.Semantic proximity Read ↗

The molecular genetics of cardiovascular disease: clinical implications.Semantic proximity Read ↗

Genetics-Current and Future Role in the Prevention and Management of Coronary Artery Disease.Semantic proximity Read ↗

Genetics of coronary artery disease and myocardial infarction--2013.Semantic proximity Read ↗

Genetic Risk Factors Related to Coronary Artery Disease and Role of Transforming Growth Factor Beta 1 Polymorphisms.Semantic proximity Read ↗

Disconnect Between Genes Associated With Ischemic Heart Disease and Targets of Ischemic Heart Disease Treatments.Semantic proximity Read ↗

Genetics of coronary heart disease: towards causal mechanisms, novel drug targets and more personalized prevention.Semantic proximity Read ↗

Genetic causality of circulating inflammatory proteins and plasma metabolites in coronary atherosclerosis.Semantic proximity Read ↗

The interleukin-1 cluster, dyslipidaemia and risk of myocardial infarction.Semantic proximity Read ↗

Inflammation and coronary artery disease: insights from genetic studies.Semantic proximity Read ↗

Genetic effects of inflammatory cytokines on coronary artery disease and myocardial infarction and the mediating roles of lipid traits.Semantic proximity Read ↗

The genetics of coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.