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Article

Aberrant methylation of the HRPT2 gene in parathyroid carcinoma.

The Annals of otology, rhinology, and laryngology - 1 Dec 2007

Hewitt Kimberly M, Sharma Pramod K, Samowitz Wade, Hobbs Maurine

Abstract excerpt

OBJECTIVES: The incidence of parathyroid carcinoma in hyperparathyroidism-jaw tumor syndrome (HPT-JT) is reported to be as high as 15%. We used a methylation-specific polymerase chain reaction (MS-PCR) technique to investigate whether hypermethylation is one mechanism of HRPT2 gene inactivation in parathyroid tumors. METHODS: DNA was extracted from samples of parathyroid tumors embedded in paraffin. MS-PCR was...

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Identifiers

PMID: 18217513
DOI: 10.1177/000348940711601210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Aberrant methylation of the HRPT2 gene in parathyroid carcinoma.PMID 18217513Read ↗

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