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Article

HRPT2 mutational analysis of typical sporadic parathyroid adenomas.

The Journal of clinical endocrinology and metabolism - 1 Sept 2005

Krebs Linda J, Shattuck Trisha M, Arnold Andrew

Abstract excerpt

CONTEXT: Mutations of HRPT2 are frequent in sporadic parathyroid carcinomas and central to their pathogenesis. However, the potential diagnostic utility of HRPT2 mutation status to distinguish between parathyroid carcinoma and adenoma hinges on the frequency of HRPT2 mutations in benign adenomas. Even a low rate of HRPT2 mutation in adenomas would greatly alter diagnostic specificity, because adenomas are far...

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Identifiers

PMID: 15956079
DOI: 10.1210/jc.2005-0717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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