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Article

Upregulation of FGFR1 expression is associated with parathyroid carcinogenesis in HPT-JT syndrome due to an HRPT2 splicing mutation.

International journal of oncology - 1 Aug 2014

Lee Ji-Young, Kim Su Yeon, Mo Eun-Yeong, Kim Eun-Sook, Han Je-Ho, Maeng Lee-So, Lee An-Hee, Eun Jung Woo, Nam Suk Woo, Moon Sung-Dae

Abstract excerpt

Mutations of the HRPT2 gene, which are responsible for hyperparathyroidism-jaw tumor (HPT-JT) syndrome, have been implicated in the development of a high proportion of parathyroid carcinomas. The aim of this study was to investigate differences in expression of the most important genes connected with parathyroid carcinoma between HPT-JT syndrome due to an HRPT2 splicing mutation, normal parathyroid tissue and...

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Source

Identifiers

PMID: 24889687
DOI: 10.3892/ijo.2014.2477

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Upregulation of FGFR1 expression is associated with parathyroid carcinogenesis in HPT-JT syndrome due to an HRPT2 splicing mutation.PMID 24889687Read ↗

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