Article
Evolution of methicillin-resistant Staphylococcus aureus towards increasing resistance.
The Journal of antimicrobial chemotherapy - 1 Mar 2014
Strommenger Birgit, Bartels Mette Damkjær, Kurt Kevin, Layer Franziska, Rohde Susanne Mie, Boye Kit, Westh Henrik, Witte Wolfgang, De Lencastre Herminia, Nübel Ulrich
Abstract excerpt
OBJECTIVES: To elucidate the evolutionary history of Staphylococcus aureus clonal complex (CC) 8, which encompasses several globally distributed epidemic lineages, including hospital-associated methicillin-resistant S. aureus (MRSA) and the highly prevalent community-associated MRSA clone USA300. METHODS: We reconstructed the phylogeny of S. aureus CC8 by mutation discovery at 112 genetic housekeeping loci from...
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