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Article

Variation in age at ESRD in autosomal dominant polycystic kidney disease.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Feb 2008

Reed Berenice Y, McFann Kim, Bekheirnia Mir R, Reza Bekheirnia M, Nobakhthaghighi Niloofar, Nobkhthaghighi Niloofar, Masoumi Amirali, Johnson Ann M, Shamshirsaz Alireza A, Shamshiraz Alireza Abdollah, Kelleher Catherine L, Schrier Robert W

Abstract excerpt

BACKGROUND: Heterogeneity manifest as more severe disease in successive generations has been attributed to genetic anticipation in patients with autosomal dominant polycystic kidney disease (ADPKD). We evaluated variation in age at end-stage renal disease (ESRD) in ADPKD families for evidence of anticipation. STUDY DESIGN: Retrospective. SETTING & PARTICIPANTS: 413 families with ADPKD seen at our single center...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18215695
DOI: 10.1053/j.ajkd.2007.10.037
PMCID: PMC2747334

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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