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Article

Affected parent sex and severity of autosomal dominant polycystic kidney disease: a retrospective cohort study .

Clinical nephrology - 1 Mar 2018

Nowak Kristen L, Chonchol Michel, You Zhiying, Gupta Malika, Gitomer Berenice

Abstract excerpt

OBJECTIVE: Parental inheritance may differentially affect autosomal dominant polycystic kidney disease (-ADPKD) severity via genetic imprinting or in utero epigenetic modifications; however, evidence is inconsistent. We conducted a longitudinal retrospective cohort study to assess the association between sex of the affected parent and time to hypertension diagnosis, end-stage renal disease (ESRD), and death in...

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Identifiers

PMID: 29035198
DOI: 10.5414/CN109247
PMCID: PMC6102561

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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