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Article

Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptors

21 Jan 2008

Abstract excerpt

A number of human and animal herpes viruses encode G-protein coupled receptors with seven transmembrane (7TM) segments-most of which are clearly related to human chemokine receptors. It appears, that these receptors are used by the virus for immune evasion, cellular transformation, tissue targeting, and possibly for cell entry. In addition, many virally-encoded chemokine 7TM receptors have been suggested to be...

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PMID: 18204488
DOI: 10.1038/sj.bjp.0707660

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