Article
Structure and molecular dynamics simulation of archaeal prefoldin: the molecular mechanism for binding and recognition of nonnative substrate proteins.
Journal of molecular biology - 29 Feb 2008
Ohtaki Akashi, Kida Hiroshi, Miyata Yusuke, Ide Naoki, Yonezawa Akihiro, Arakawa Takatoshi, Iizuka Ryo, Noguchi Keiichi, Kita Akiko, Odaka Masafumi, Miki Kunio, Yohda Masafumi
Abstract excerpt
Prefoldin (PFD) is a heterohexameric molecular chaperone complex in the eukaryotic cytosol and archaea with a jellyfish-like structure containing six long coiled-coil tentacles. PFDs capture protein folding intermediates or unfolded polypeptides and transfer them to group II chaperonins for facil...
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