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Article

Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation.

Journal of hepatology - 1 Dec 2005

Fung Scott K, Andreone Pietro, Han Steve H, Rajender Reddy K, Regev Arie, Keeffe Emmet B, Hussain Munira, Cursaro Carmela, Richtmyer Pamela, Marrero Jorge A, Lok Anna S F

Abstract excerpt

BACKGROUND/AIMS: The susceptibility of adefovir-resistant hepatitis B virus (HBV) mutants is only reduced by 3-10-fold in in vitro studies, suggesting that virologic breakthrough and clinical deterioration are unlikely. The aim of this study was to describe the clinical course of patients with adefovir-resistant HBV infection. METHODS: Testing for adefovir-resistant mutations was performed on patients who had a...

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Identifiers

PMID: 16168522
DOI: 10.1016/j.jhep.2005.05.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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