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Article

Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation.

Journal of hepatology - 1 Dec 2005

Fung Scott K, Andreone Pietro, Han Steve H, Rajender Reddy K, Regev Arie, Keeffe Emmet B, Hussain Munira, Cursaro Carmela, Richtmyer Pamela, Marrero Jorge A, Lok Anna S F

Abstract excerpt

BACKGROUND/AIMS: The susceptibility of adefovir-resistant hepatitis B virus (HBV) mutants is only reduced by 3-10-fold in in vitro studies, suggesting that virologic breakthrough and clinical deterioration are unlikely. The aim of this study was to describe the clinical course of patients with ad...

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Source

Identifiers

PMID: 16168522
DOI: 10.1016/j.jhep.2005.05.037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16168522-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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