Article
Characteristics of the env genes of HIV type 1 quasispecies in long-term nonprogressors with broadly neutralizing antibodies.
Journal of acquired immune deficiency syndromes (1999) - 1 Mar 2008
Braibant Martine, Agut Henri, Rouzioux Christine, Costagliola Dominique, Autran Brigitte, Barin Francis
Abstract excerpt
Primary isolates of different subtypes of HIV-1 can be neutralized in vitro by the broadly neutralizing antibodies (NAbs) found in the sera of a small number of HIV-1-infected patients. This broad response is most frequent in long-term nonprogressors (LTNPs). We investigated whether the presence of NAbs in the sera of some LTNPs was associated with particular properties of the envelope glycoproteins of the...
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