Article
Early events in the pathogenesis of epithelial ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Feb 2008
Landen Charles N, Birrer Michael J, Sood Anil K
Abstract excerpt
Ovarian carcinogenesis, as in most cancers, involves multiple genetic alterations. A great deal has been learned about proteins and pathways important in the early stages of malignant transformation and metastasis, as derived from studies of individual tumors, microarray data, animal models, and inherited disorders that confer susceptibility. However, a full understanding of the earliest recognizable events in...
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