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Physical, social and productive leisure activities, cognitive decline and interaction with APOE-epsilon 4 genotype in Chinese older adults.

International psychogeriatrics - 1 Apr 2008

Niti Matthew, Yap Keng-Bee, Kua Ee-Heok, Tan Chay-Hoon, Ng Tze-Pin

Abstract excerpt

BACKGROUND: We evaluated the combined and differential effects of physical, social and productive activities on cognitive decline and whether they were modified by the presence of the APOE-epsilon 4 allele. METHODS: In a prospective cohort study of 1635 community-dwelling Chinese older adults aged 55 or older participating in the ongoing Singapore Longitudinal Aging Study, physical, social and productive leisure...

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Source

Identifiers

PMID: 18190728
DOI: 10.1017/S1041610207006655

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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