Article
Tissue-specific requirements for specific domains in the FERM protein Moe/Epb4.1l5 during early zebrafish development.
BMC developmental biology - 11 Jan 2008
Christensen Arne K, Jensen Abbie M
Abstract excerpt
BACKGROUND: The FERM domain containing protein Mosaic Eyes (Moe) interacts with Crumbs proteins, which are important regulators of apical identity and size. In zebrafish, loss-of-function mutations in moe result in defects in brain ventricle formation, retinal pigmented epithelium and neural retinal development, pericardial edema, and tail curvature. In humans and mice, there are two major alternately spliced...
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