Advances in Neuronal Cell Death 2007

Abstract excerpt

In a stroke lesion, there is a core of necrotic cell deathsurrounded by a zone of tissue at risk, termed the penum-bra. In the penumbra, there is usually less severe tissue damage. Programmed cell death (PCD) pathways have been documented to be present in the penumbra. While many studies have used the term apoptosis as equivalent to PCD, the absence of complete biochemical and morphological characteristics of...

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