Caspase requirement for neuronal apoptosis and neurodegeneration.

Abstract excerpt

The execution of the apoptotic programme involves a relatively few pathways that converge on activation of the caspase family of proteases. However, increasing evidence indicates that apoptotic-like features can be found also when cells are treated with inhibitors of caspases. This has posed questions as to whether death with apoptotic features can still occur in a caspase-independent way, and whether caspase...

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