Article
Reversal of myofibroblasts by amniotic membrane stromal extract.
Journal of cellular physiology - 1 Jun 2008
Li Wei, He Hua, Chen Ying-Ting, Hayashida Yasutaka, Tseng Scheffer C G
Abstract excerpt
Myofibroblasts play an important role in morphogenesis, inflammation, and fibrosis in most tissues. The amniotic membrane stroma can maintain keratocytes in cultures and prevent them from differentiating into myofibroblasts. However, it is unknown whether the AM stroma can also reverse differentiated myofibroblasts. In this study, we found that amniotic membrane stromal cells (AMSCs), which adopted fibroblastic...
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