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Article

Modulation of longevity-associated genes by estrogens or phytoestrogens

6 Jan 2008

Abstract excerpt

Females live longer than males. We have shown that the higher levels of estrogens in females protect them against aging, by up-regulating the expression of antioxidant, longevity-related genes, such as that of selenium-dependent glutathione peroxidase (GPx) and Mn-superoxide dismutase (Mn-SOD). Both estradiol and genistein (the most abundant phytoestrogen in soybeans) share chemical properties which confer...

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Identifiers

PMID: 18177268
DOI: 10.1515/bc.2008.027

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