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Article

A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

6 Jan 2008

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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18176557
DOI: 10.1038/nchembio.63

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A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complexPMID 18176557Read ↗

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Identification of Novel Radiosensitizers in a High-Throughput, Cell-Based Screen for DSB Repair InhibitorsSemantic proximity Read ↗

MRE11/RAD50/NBS1: complex activitiesSemantic proximity Read ↗

Base excision repair and design of small molecule inhibitors of human DNA polymerase βSemantic proximity Read ↗

Human RAD50 deficiency: Confirmation of a distinctive phenotype.Semantic proximity Read ↗

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitorsSemantic proximity Read ↗

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Biochemical and structural characterization of analogs of MRE11 breast cancer-associated mutant F237C.Semantic proximity Read ↗

Targeting homologous recombination, new pre-clinical and clinical therapeutic combinations inhibiting RAD51Semantic proximity Read ↗

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