Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in CYP17 and endometrial cancer risk.

Human genetics - 1 Mar 2008

Gaudet Mia M, Lacey James V, Lissowska Jolanta, Peplonska Beata, Brinton Louise A, Chanock Stephen, Garcia-Closas Montserrat

Abstract excerpt

Genetic variation in CYP17 is suspected to be related to endometrial cancer risk based on its role in the regulation of steroid and non-steroid hormone biosynthesis. Reported associations between CYP17 and higher levels of estradiol in some studies suggest that the C allele of a T-to-C single nuc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

Share to Meta-Analysis as Topic

Share to Poland

Share to Postmenopause

Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 18172694
DOI: 10.1007/s00439-007-0454-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18172694-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in CYP17 and endometrial cancer risk.PMID 18172694Read ↗

Genetic variation of the CYP17 and susceptibility to endometrial cancer: a meta-analysis.Semantic proximity Read ↗

A polymorphism in CYP17 and endometrial cancer risk.Semantic proximity Read ↗

CYP17A1 T-34C polymorphism is not associated with endometrial cancer risk.Semantic proximity Read ↗

CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review.Semantic proximity Read ↗

Genetic polymorphisms and endometrial cancer risk.Semantic proximity Read ↗

The T/C polymorphism of the CYP17 gene and G/A polymorphism of the CYP19 gene in endometrial cancer.Semantic proximity Read ↗

Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk.Semantic proximity Read ↗

Variants in estrogen biosynthesis genes, sex steroid hormone levels, and endometrial cancer: a HuGE review.Semantic proximity Read ↗

Genome-wide association study identifies a common variant associated with risk of endometrial cancer.Semantic proximity Read ↗

Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer.Semantic proximity Read ↗

CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

The CYP17 MspA1 polymorphism is not associated with an increased risk of uterine leiomyomas in a Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.