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Article

Radiotherapy in lung adenocarcinoma with brain metastases: effects of activating epidermal growth factor receptor mutations on clinical response.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2008

Gow Chien-Hung, Chien Chun-Ru, Chang Yih-Leong, Chiu Yueh-Hsia, Kuo Sung-Hsin, Shih Jin-Yuan, Chang Yeun-Chung, Yu Chong-Jen, Yang Chih-Hsin, Yang Pan-Chyr

Abstract excerpt

PURPOSE: Whole-brain radiation therapy (WBRT) has been applied to inoperable brain metastases in lung adenocarcinoma. Recently, an in vitro study showed reduced clonogenic survival of mutant epidermal growth factor receptor (EGFR) lung cancer cell lines in response to ionizing radiation compared...

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PMID: 18172267
DOI: 10.1158/1078-0432.CCR-07-1468

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18172267-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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